Talking to Your Patients About SYMLIN

The following are important topics you should discuss with your patients about SYMLIN® (pramlintide acetate) injection:

Discuss the Risk of Hypoglycemia

Discuss the risk and consequences of hypoglycemia and approaches to minimize its occurrence.

Inform patients about the importance of self-management practices including glucose monitoring and timing of dosing. In addition, reinforce the importance of adherence to meal planning, physical activity, recognition and management of hypoglycemia and hyperglycemia, and assessment of diabetes complications.

Never Share a SymlinPen Between Patients

Advise patients that they should never share a SymlinPen with another person, even if the needle is changed, because doing so carries a risk for transmission of blood-borne pathogens.

Never Mix SYMLIN and Insulin

Inform patients that SYMLIN and insulin should always be administered as separate injections and never be mixed.

Show patients how to administer SYMLIN using the pen-injector. Advise patients to use a new needle for each injection.

Remember to Instruct your Patients

Inform patients of the potential risks and advantages of SYMLIN therapy. Advise women with diabetes to inform their healthcare professional if they are pregnant or contemplating pregnancy.

Instruct patients on the proper injection technique and proper storage of SYMLIN. Instruct patients on handling of special situations such as intercurrent conditions (illness or stress), an inadequate or omitted insulin dose, inadvertent administration of increased insulin or SYMLIN dose, inadequate food intake or missed meals.

Refer patients to the SYMLIN Medication Guide and Patient Instructions for Use for additional information.


Your patients may have questions about how to use SYMLIN.

  • Information about how to prepare and inject SYMLIN using the SymlinPen is provided in the Instructions for Use included with each pen:
  • Patients can also speak with a trained professional about using the SymlinPen by calling the toll-free support line at 1-888-SYMLIN-1 (1-888-796-5461).

Your patients may also want to learn about how they may be able to save on their SYMLIN prescription.

AstraZeneca is committed to assisting appropriate patients with diabetes by offering savings on SYMLIN. The MySavingsRx Card can help eligible patients qualify for assistance with out-of-pocket copay costs. Eligibility requirements and terms of use apply. Visit to learn more.

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